ANGIO-SEAL® Vascular Closure Devices

Active closure for rapid and reliable hemostasis proven to accelerate patient mobility and
enable same-day discharge1

  • Resorbable components provide immediate closure with uncompromised blood flow1-3
  • Lower bleeding complication rates compared to other  hemostasis strategies4
  • Manual compression not required for reinforcement of the closure
  • Active closure using bioabsorbable anchor and collagen with 99.7% deployment success5
  • Bioabsorbable ANGIO-SEAL is no longer visible 30 days following implantation*

EuroIntervention. Vol 5. Tellez A, Cheng Y, Yi G, et al. In vivo intravascular ultrasound analysis of the absorption rate of the Angio-Seal™ vascular closure device in the porcine femoral artery:731-736. 


610130 6Fr 0.035
610131 8Fr 0.038

ANGIO-SEAL® Evolution

C610134 6Fr 0.035
C610135 8Fr 0.038


  1. Kapadia SR, Raymond R, Knopf W, et al. Am J Cardiol. 2001;87:789-791.
  2. Nash JE, Evans DG. Herz. 1999;24(8):597-606.
  3. Angio-Seal™ ST Plus, Angio-Seal™ VIP and Angio-Seal™ Evolution Instructions for Use.
  4. Tavris D. J Invasive Cardiol. 2012;24(7):2-8.
  5. Applegate RJ, Turi Z, Sachdev N, et al. J Invasive Cardiol. 2010;22(9):420-6.


The  Angio-Seal Vascular Closure Device product family, including the STS Plus, VIP and Evolution platforms, is indicated for use in closing and reducing time to hemostasis of the femoral arterial puncture site in patients who have undergone diagnostic angiography procedures or interventional procedures using an 8 French or smaller procedural sheath for the 8 F Angio-Seal device and a 6 French or smaller procedural sheath for the 6 F Angio-Seal device. The Angio-Seal STS Plus, VIP and Evolution platform devices are also indicated for use to allow patients who have undergone diagnostic angiography to safely ambulate as soon as possible after sheath removal and device placement, as well as to allow patients who have undergone an interventional procedure to safely ambulate after sheath removal and device placement.

Important Safety Information:

Possible adverse events for vascular closure devices include, but are not limited to: bleeding or hematoma, AV fistula or pseudoaneurysm, infection, allergic reaction, foreign body reaction, inflammation or edema. This device should only be used by a licensed physician (or other health care professional authorized by or under the direction of such physician) possessing adequate instruction in the use of the device, e.g., participation in an Angio-Seal physician instruction program or equivalent.

RX ONLY. The advertisement is directed to physicians only, and not to consumers. Refer to product labels and packaging insert for complete warnings, precautions, potential complications, and instructions for use. Products may not have regulatory approval in all countries. Please contact your local sales representative if you have questions about the availability of products in your area.